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HUMAN CHYMASE INHIBITORS

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专利名称:HUMAN CHYMASE INHIBITORS发明人:TSUCHIYA, NAOKI,MATSUMOTO,

YOSHIYUKI,SAITOU, HIROSHI,MIZUNO,TSUYOSHI

申请号:EP01901398申请日:20010117公开号:EP1167360A9公开日:20020515

摘要:The present invention provides a benzimidazole derivative or its

pharmaceutically permissible salt expressed by the following formula (1). Further, thepresent invention provides a human chymase activity inhibitor containing the substance asan active ingredient. (the ring marked with A expresses a pyridine ring or a benzene ring;X and X are each a hydrogen atom, a halogen atom, a trihalomethyl group, a cyanogroup, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkoxygroup, or the like; B is a substituted or unsubstituted alkylene group, or the like; E is -COOR or the like; G is a substituted or unsubstituted alkylene group; J is a substituted orunsubstituted alkyl group, or a substituted or unsubstituted aryl group; and M is a sulfuratom, sulfoxide, sulfone or the like).

申请人:TEIJIN LIMITED

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