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专利名称：Method for detection of gram-negative
bacterial liposaccharides in biological fluids
发明人：Eric J. Hansen,Robert S. Munford,Jussi
Mertsola
申请号：US07/972498申请日：19930205公开号：US05356778A公开日：19941018
摘要：The invention relates to a method of detecting gram-negative bacterialendotoxin using antibody capture combined with amoebocyte lysate chromogenicdetection. The method is highly sensitive and rapid and may be used for detection ofspecific endotoxin. In a particular application, picogram levels of Haemophilus influenzaetype b endotoxin are detected in plasma taken from previously infected mammals. Inanother particular application, the method is applied to the detection and diagnosis ofdisease, through the detection of endotoxin from disease- causing organisms. A specificexample is the diagnosis of chancroid through the detection of endotoxin from H.ducreyi.
申请人：BOARD OF REGENTS, THE UNIVERSITY OF TEXAS
代理机构：Arnold, White & Durkee
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